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Advanced Vaccine Research Methods for the Decade of Vaccines

Advanced Vaccine Research Methods for the Decade of Vaccines

Since the publication of Vaccine Design: Innovative Approaches and Novel Strategies in 2011, the field of vaccinology has advanced significantly. The application of new sophisticated 'omics' technologies and the use of pioneering approaches have yielded a wealth of new data. This new book aims to distill the most important new findings to provide a timely overview of the field.

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Publisher:     Caister Academic Press
Editor:           Fabio Bagnoli and Rino Rappuoli Novartis Vaccines, Via Fiorentina 1, 53100 Siena, Italy
Publication date: April 2015 (hardback); Feb 2015 (ebook)
Pages: c. 456
Hardback: ISBN 978-1-910190-03-6 £180


Written by leading experts in the field, each chapter affords a critical insight to a particular topic, reviews current research, discusses future direction and aims to stimulate discussion. The provision of extensive reference sections in the chapters positively encourages readers to pursue the subject in greater detail.

We have retained the same format of our 2011 book and divided the book into two main parts. The first explores in considerable depth the key innovations that we think are dramatically changing the field; both for preclinical as well as clinical vaccine research fields. Some of the topics covered include: the use of deep sequencing, cellular screens to interrogate the human T and B cell repertoires, comparative genomics to track bacterial pathogens, quantitative proteomics, structural biology, novel strategies for vaccine administration, T-cell inducing vaccines, etc. The second part focuses on diseases for which current medical treatment is not very effective and disease that could be either prevented or treated by vaccination. The examples that we have used comprise very different diseases; we include not only infectious diseases (e.g. caused by bacteria), but also cancer. We believe that these will be the vaccines of the future, the 'vaccines for 2020'.

This books is essential reading for everyone working in vaccine R and D in academia, biotechnology companies, and the pharmaceutical industry and a recommended volume for all microbiology libraries.




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