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Anaerobic Parasitic Protozoa: Genomics and Molecular Biology

Anaerobic Parasitic Protozoa: Genomics and Molecular Biology

In this book internationally acclaimed researchers critically review the most important aspects of research on anaerobic parasitic protozoa, providing the first coherent picture of their genomics and molecular biology since the publication of the genomes.

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£159.00

9781904455615

Availability: Please note: We cannot supply this book to the USA or Canada. Please visit http://usa.caister.com


Publisher: Caister Academic Press
Editors: C. Graham Clark1, Patricia J. Johnson2 and Rodney D. Adam3
1Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine London WC1E 7HT, UK; 2Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, USA; 3Department of Immunobiology, University of Arizona College of Medicine, Tucson AZ, USA 
Publication date: March 2010
ISBN: 978-1-904455-61-5
Pages: x + 222

Anaerobic parasitic protozoa cause medically and economically important diseases such as dysentery, sexually transmitted infections, and gastroenteritis that affect millions of people worldwide annually. Recently the genomes of the three key anaerobic protozoa, TrichomonasGiardiaand Entamoeba, have been determined. The availability of these genomic data and the use of post-genomic analyses have provided fascinating new insights into the biology of these important parasites. They will be important for the design of novel anti-protozoan drugs and the development of effective vaccines.

In this book internationally acclaimed researchers critically review the most important aspects of research on anaerobic parasitic protozoa, providing the first coherent picture of their genomics and molecular biology since the publication of the genomes. Chapters are written from a molecular and genomic perspective and contain speculative models upon which future research efforts can be based. Topics include: the genomes of Entamoeba histolyticaTrichomonas vaginalisGiardia and other diplomonads; the cytoskeletons of Entamoeba histolyticaGiardia lamblia and Trichomonas vaginalis; genomic analyses and manipulation of gene expression in Entamoeba histolytica; nuclear and chromosomal structure and replication inGiardia; and the mitochondrion-like organelles of a fourth anaerobe, Blastocystis.

Essential reading for all researchers working with these protozoa and related organisms and with eukaryotic model organisms. Recommended text for all parasitology laboratories.

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